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Robinson annelation reaction
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Robinson annelation reaction
conjugated adition reaction or Michael addition reaction followed by intermolecular aldol and dehydration process is called Robinson annelation reaction
in Robinson annelation reaction since the cyclisation involve hence always thermodynamically controlled enolate ion formed initially and major product is dehydration product.
since the Robinson annelation reaction is always thermodynamically controlled so we cannot obtain kinetically controlled less substituted product
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