LDA regent,LDA reaction with carbonyl compound,LDA reaction with ester,LDA reaction with alkyl halideLDA/PhSeBr/H2O2 reagent,LDA/ MeI with carbonyl compound LDA/PhCho reagent,

LDA strong base and it is not nucleophile.

solvent :generally tetrahydrofuran solvent is used.



LDA can abstract less acidic proton as well as strong acidic proton.

the structure of LDA is
the structure of LDA



LDA abstract proton from Alpha position for carbonyl.

LDA  abstract proton from allylic position of alkane.





applications of LDA


LDA reaction with carbonyl compound
LDA reaction with carbonyl compound





LDA reaction with alkene
LDA reaction with alkene


LDA  reaction with ester
LDA  reaction with ester


LDA  reaction with alkyl halide


LDA  reaction with alkyl halide


LDA/PhSeBr/H2O2 reagent
LDA/PhSeBr/H2O2 reagent



LDA/ MeI with carbonyl
LDA/ MeI with carbonyl


LDA/PhCho reagent


LDA/PhCho reagent

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