Gilmann reagent(R2culi)

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Gilmann reagent 

gilmann reagent is a organocopper agent 
it is a source of  nucleophile
 it works at minus 78 degree temperature 

preparation of gilmann reagent

preparation of gilmann reagent


 application of gilman reagent 

1.substitution reaction with alkyl halide (corey house synthesis)
core house synthesis by gimann reagent


2.epoxide ring opening
epoxide ring opening by gimann reagent


3.nucleophilic addition reaction( Michael addition)
Michael addition by gilmann reagent


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